The discovery of slimming capsules which made spending hours in a workout room and alpilean Video following a rigorous dieting program redundant to a certain extent, made a rage in the market. They turned out to become a blessing in disguise for the entire pharmaceutical industry, that is modern earning of significant revenues with the purchase of these drugs. It has been estimated that more than 20 million of Americans consume diet plan tablets on an annual basis.
The History of Diet Pills It was during the ten years of 1950s when science and medicine had been creating striking accomplishments that these pills had been initially recommended by the doctors to the patients. The physicians recommended amphetamines, a drug moved to the World War II to keep soldiers alert and productive, for weight loss objective. Among the unwanted side effects of amphetamines was appetite suppression which led doctors in prescribing them as diet pills. Soon many weight loss individuals underwent amphetamines led substance abuse issues as well as its prescription was inhibited. It was in 1970s when health consciousness sprung up to the pinnacle of its and fitness became a world wide craze. Weight reduction became the title of the game and the pharmaceutical industry saw a sudden boom in the demand for them. The first such drugs in this era were essentially amphetamines derivatives, otherwise known as "speed". Later, a variety of fat reduction pills flooded the market. Food as well as Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that had been followed by dexfenfluramine (Redux) in 1996. After that came the diet drug Phentermine, a sympathomimetic appetite suppressant, which was approved by the FDA in 1997. Many medical professionals prescribed Phentermine in conjunction with fenfluramine. The combined prescription of both drugs was aptly named fen phen. The era of fen-phen quickly declined with reports of heart valve disease resulting from the combined use of both the prescription drugs began to surface. The manufacturers withdrew dexfenfluramine as well as fenfluramine from the market, thereby ending the rule of fen-phen. The most popular weight minimization drugs that are given in the US are sympathomimetic appetite suppressants like Phentermine. These medications affect the neurotransmitters in such a way that brings about a loss in appetite. Many other weight loss supplements that received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 as well as 2001 respectively. While Orlistat is a lipase inhibitor which inhibits the absorption of dietary fats to the body, Sinutramine acts on mind through serotonin, norepinephrine as well as dopamine reuptake inhibition.